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Retinal OCT Imaging System to Incorporate Adaptive Optics

Watertown, Mass. – April 10, 2006:   Physical Sciences Inc. has selected a deformable mirror from Boston Micromachines for use in its adaptive optics spectral domain optical coherence tomography (AO-SDOCT) system. The combination of AO and SDOCT enables better imaging of the human retina.
  Optical coherence tomography is an interferometric technique that uses infrared light to produce a penetrating image of biological tissue, rather like ultrasound imaging but at much higher spatial resolution.

In the past, researchers and clinicians have been unable to see critical features in the human retina due to ocular aberrations that limited imaging resolution. Adaptive optics aberration compensation will enable better resolution imaging of the human retina than ever before. This improvement in image quality will allow clinicians using the AO-SDOCT system to detect and diagnose diabetic retinopathy and macular degeneration as well as to determine the efficacy of drugs in drug studies.

The selected deformable mirror is Boston Micromachines' Multi-DM, a 12×12 actuator micro-electro-mechanical mirror. “The Multi-DM has
Atlas of Laser Scanning Ophthalmoscopy, Scheuerle
proven reliability and high performance,” said Dr. Daniel X. Hammer, Principal Research Scientist at Physical Sciences Inc. “Our previous success integrating a BMC deformable mirror into our adaptive optics scanning laser ophthalmoscope (AOSLO) led to our decision to build the AO-SDOCT with a BMC mirror.” According to BMC, The Multi-DM boasts a longer stroke than other mirrors, which enables the correction of larger aberrations of the human eyes. This allows clinicians to image a higher percentage of patients with both better and worse eyes to advance the understanding, diagnosis, and treatment of eye pathologies.
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© 2006
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Optical Coherence Tomography, Bouma 'Surely You're Joking, Mr. Feynman!', Feynman